Cmin (Minimum Concentration)

Cmin, or minimum concentration, refers to the lowest amount of a medication in a patient's bloodstream during a dosing period. It is important because it helps ensure the drug stays above a certain level needed to be effective, without dropping too low and losing its beneficial effect. Monitoring Cmin allows healthcare providers to adjust doses, maintaining the right balance between effectiveness and safety. For medications with narrow safety margins, keeping the Cmin within a target range is essential to prevent treatment failure or adverse effects. In essence, Cmin indicates the lowest drug level the body has between doses.