Claudin proteins

Claudin proteins are a family of specialized molecules that form tight junctions between cells, especially in tissues like the skin, gut, and blood vessels. These tight junctions act as barriers, regulating what substances can pass between cells and maintaining tissue integrity. By controlling permeability, claudins help ensure that nutrients, ions, and fluids move properly while preventing harmful substances from slipping through. Different types of claudins can make the barrier more or less restrictive, which is crucial for normal tissue function and response to health or disease.