Classical Ehlers-Danlos Syndrome

Classical Ehlers-Danlos Syndrome (cEDS) is a genetic connective tissue disorder primarily affecting the skin and joints. It results from mutations that weaken collagen, a protein vital for skin elasticity and tissue strength. People with cEDS often have very stretchy, fragile skin that easily bruises and scars. They may also experience hyperflexible joints that can dislocate or be unstable. While the syndrome varies among individuals, common features include soft skin, easy bruising, joint hypermobility, and slow wound healing. Although it can cause some health challenges, many individuals manage symptoms effectively with medical care and lifestyle adjustments.