Circular consensus sequencing

Circular consensus sequencing (CCS) is a method used in DNA analysis that improves accuracy by repeatedly reading the same DNA molecule. In this process, a circular DNA strand is passed through a sequencing device multiple times, generating multiple readings of the same sequence. These repeated reads are then combined to create a highly accurate consensus sequence, reducing errors common in single reads. CCS is particularly useful for detecting rare genetic variations and obtaining precise DNA information, making it valuable in research, diagnostics, and personalized medicine.