Chronobiology of Asthma

Chronobiology of asthma refers to how the condition varies according to the body's natural biological rhythms, especially over the 24-hour day. Asthma symptoms, such as wheezing and shortness of breath, tend to worsen in the early morning hours, typically between 2 and 4 a.m., due to fluctuations in hormone levels, airway inflammation, and airway muscle tone. Understanding these patterns helps in timing medication and managing symptoms more effectively. Recognizing the daily biological cycle allows healthcare providers to tailor treatments to reduce nighttime symptoms and improve overall asthma control.