Chromosome instability

Chromosome instability refers to the increased likelihood of changes or errors in a cell's genetic material during cell division. Normally, chromosomes are accurately copied and evenly distributed, but instability can cause the loss, gain, or rearrangement of genetic segments. This can lead to abnormal cell behavior, including uncontrolled growth or cell death, and is associated with various diseases, particularly cancer. Essentially, chromosome instability disrupts the normal genetic balance, making cells more prone to mutations and genetic diversity, some of which may contribute to disease progression.