chiral switch

A chiral switch involves changing a drug from using its mixture of two mirror-image forms (enantiomers) to solely using one of these forms, or enantiomers. Enantiomers can behave differently in the body—some may be more effective or cause fewer side effects. By switching to a single enantiomer, developers aim to improve the drug’s potency, reduce adverse effects, and enhance safety. This process helps make treatments more targeted and efficient, often leading to better patient outcomes and sometimes lower doses needed.