Chemotherapy-Induced Peripheral Neuropathy (CIPN)

Chemotherapy-Induced Peripheral Neuropathy (CIPN) is a common side effect of certain cancer treatments where chemotherapy damages peripheral nerves—the nerves outside the brain and spinal cord. This damage can cause symptoms such as numbness, tingling, burning sensations, weakness, or pain, usually in the hands and feet. The symptoms result from nerve fibers being affected, which disrupts normal nerve signaling. CIPN can impact daily activities and quality of life, and its severity varies among individuals. While adjustments to chemotherapy can help manage symptoms, CIPN can sometimes persist even after treatment ends.