Image for CHD3 (also known as Mi-2)

CHD3 (also known as Mi-2)

CHD3, also known as Mi-2, is a protein that plays a key role in regulating how genes are turned on or off within our cells. It is part of a complex called the nuRD (Nucleosome Remodeling and Deacetylase) complex, which helps organize DNA and control gene activity by modifying the structure of chromatin (the combination of DNA and proteins). Proper function of CHD3 is essential for normal development, cell growth, and differentiation. Mutations or disruptions in CHD3 can lead to developmental disorders, highlighting its importance in maintaining healthy cellular processes.