CGRP (calcitonin gene-related peptide) inhibitors

CGRP inhibitors are medications designed to prevent migraines by blocking calcitonin gene-related peptide (CGRP), a molecule involved in transmitting pain and dilating blood vessels during a migraine. During a migraine, CGRP levels rise, contributing to symptoms. These inhibitors, such as certain antibodies, attach to CGRP or its receptors, reducing its effects and helping to decrease the frequency and severity of migraines. They are targeted treatments typically used when other medications are ineffective, offering a new approach to managing chronic migraine pain with fewer side effects than traditional therapies.