Centrosome Biogenesis

Centrosome biogenesis is the process by which cells produce the centrosome, a structure that organizes microtubules essential for cell division and shape. Typically, a cell inherits a centrosome composed of two centrioles surrounded by a matrix of proteins. During cell division, the centrosomes duplicate so each new cell receives one, ensuring proper chromosome segregation. This process involves specific proteins and signaling pathways that coordinate duplication, maturation, and separation of centrosomes, maintaining cellular organization and function. Proper centrosome biogenesis is vital for healthy cell division and avoiding abnormalities like cancer.