central tolerance

Central tolerance is a process in the immune system that prevents the body from attacking its own cells. As immune cells develop, they are tested in the thymus and bone marrow. Cells that strongly react to the body's own proteins are eliminated or modified, reducing the chance of autoimmune diseases. This screening ensures only cells that recognize foreign invaders but not self are released into the bloodstream. Central tolerance is crucial for maintaining immune balance, allowing the body to defend against infections while avoiding harmful reactions against its own tissues.