CENPA

CENPA is a specialized protein found in human cells that plays a critical role in cell division. It is a variant of the histone protein H3 and is specifically located at the centromere, the central part of a chromosome. CENPA helps form the foundation for the assembly of the kinetochore, a structure that ensures chromosomes are accurately pulled apart during cell division. Proper function of CENPA is essential for maintaining genetic stability, preventing errors that could lead to cell malfunction or diseases such as cancer.