CDC73

CDC73 is a gene that provides instructions for making a protein called parafibromin, which helps regulate cell growth and prevent tumors. Mutations or changes in this gene can impair its function, leading to an increased risk of developing certain types of tumors, especially in the parathyroid glands. These genetic alterations are linked to a rare inherited condition called Hyperparathyroidism-Jaw Tumor (HPT-JT) syndrome, which can cause tumors in endocrine glands and other tissues. Understanding CDC73 is important for diagnosing and managing these associated tumors and inherited conditions.