CB2 antagonists

CB2 antagonists are substances that block the CB2 receptors in the body's endocannabinoid system, which plays a role in regulating immune response, inflammation, and pain. By inhibiting these receptors, CB2 antagonists can potentially reduce inflammation and immune activity. They are being studied for their potential to treat conditions involving excessive immune responses, such as autoimmune diseases and certain inflammatory disorders. Unlike CB1 receptors in the brain, CB2 receptors are mostly found in the immune system and peripheral tissues, so blocking them aims to modulate immune functions without significantly affecting mood or cognition.