CaV2.2 (Calcium Voltage-Gated Channel Subunit Alpha 2)

CaV2.2 is a specific type of calcium channel found in nerve cells, primarily located at nerve endings. It plays a crucial role in transmitting signals by allowing calcium ions to enter the neuron when an electrical signal arrives. This calcium influx triggers the release of neurotransmitters, which carry messages between nerve cells. Proper functioning of CaV2.2 is essential for communication within the nervous system, influencing pain perception, muscle contraction, and other critical processes. Its activity is tightly regulated, and it is a target for certain medications used to manage pain conditions.