cardiac allograft tolerance

Cardiac allograft tolerance refers to the immune system's ability to accept a transplanted heart without attacking it. When a heart is donated, the recipient’s immune defenses might see it as foreign and try to reject it. Tolerance occurs when the immune system learns to recognize the new heart as part of the body, reducing or eliminating rejection risks. Achieving this state can improve transplant success and decrease the need for lifelong immunosuppressive drugs. Researchers aim to understand and promote this tolerance to enhance patient outcomes and long-term heart transplant survival.