Calsequestrin-2 (Calsequestrin in cardiac tissue)

Calsequestrin-2 is a specialized protein found in heart cells that acts as a storage unit for calcium ions, which are essential for heart muscle contraction. It binds and holds large amounts of calcium within the sarcoplasmic reticulum, a structure inside the cell, ensuring that calcium is readily available for coordinated contractions. This regulation is vital for maintaining the heart's rhythm and strength. Proper functioning of Calsequestrin-2 helps prevent irregular heartbeats and supports healthy cardiac activity.