Calcification theories

Calcification theories explore how calcium deposits form in tissues, such as arteries or soft tissues. One view suggests that calcification occurs when cells damaged by aging, injury, or inflammation release substances that promote calcium buildup. Others propose that abnormal mineral metabolism, like high calcium or phosphate levels in the blood, leads to unwanted calcium deposits. Additionally, certain proteins and enzymes may influence the process by either promoting or inhibiting calcification. Understanding these theories helps researchers find ways to prevent or treat unwanted calcification, which is linked to conditions like cardiovascular disease and tissue hardening.