BRG1 (Brahma Related Gene 1)

BRG1, also known as SMARCA4, is a protein that plays a key role in regulating how our genes are turned on and off. It is part of a complex called SWI/SNF, which modifies the structure of DNA and its associated proteins to make certain genes accessible for activity. This process is essential for cell growth, differentiation, and response to signals. Proper functioning of BRG1 is vital for normal development, and mutations or disruptions in this gene have been linked to various cancers and developmental disorders.