Bothers Syndrome

Bother's Syndrome, also known as Bother's Disease, is a rare hereditary disorder that primarily affects blood vessels, leading to abnormal blood flow and tissue damage. It often causes symptoms like skin lesions, ulcers, and swelling, especially in the limbs. The condition results from genetic mutations that impair vascular development and repair. While the exact mechanisms are complex, it typically manifests in early adulthood and requires medical management to prevent complications. Diagnosis involves clinical evaluation and imaging studies, and treatment may include medications, lifestyle modifications, and sometimes surgery to improve circulation and reduce symptoms.