Blood-brain Barrier Disruption

The blood-brain barrier (BBB) is a protective shield that separates the brain from the bloodstream, controlling what substances can enter. Disruption of this barrier occurs when it becomes damaged or dysfunctional, allowing harmful substances, like toxins or pathogens, to enter the brain. This can lead to various neurological problems, including inflammation, infection, or neurodegenerative diseases. Factors such as trauma, infection, or certain medical conditions can cause BBB disruption, emphasizing its crucial role in maintaining brain health and function. Understanding this process is essential for developing treatments for brain-related disorders.