Biology of the interstitium

The interstitium is a network of tiny, fluid-filled spaces and connective tissues found throughout the body, especially around organs, blood vessels, and muscles. It acts as a supportive structure, allowing tissues to stretch and move smoothly while also serving as a pathway for fluids, cells, and nutrients. Recent discoveries have identified it as a dynamic, transport-rich environment, playing roles in tissue health, immune response, and possibly disease spread. Understanding the interstitium helps us better grasp how the body maintains its structure and responds to injury or illness.