BCS Class II

BCS Class II refers to a category used in pharmacology to classify drugs based on their solubility and how easily they are absorbed in the body. Specifically, Class II drugs have low solubility but high permeability, meaning they don’t dissolve well in water but can pass through biological membranes once dissolved. This can limit their absorption and effectiveness, making formulation strategies important to improve their dissolution and bioavailability. Examples include drugs like ledipasvir and atorvastatin. Proper formulation is essential to ensure these drugs work effectively when taken.