BAF subunits

BAF subunits are the individual protein components that make up the BAF complex, a crucial group of proteins involved in remodeling the structure of chromatin—how DNA is packaged in cells. This remodeling regulates gene activity, allowing certain genes to be turned on or off as needed. Each BAF subunit contributes specific functions to the complex, ensuring precise control over gene expression. Variations or mutations in these subunits can affect cellular processes and are linked to some developmental disorders and cancers. Essentially, BAF subunits work together to manage the organization of DNA within the nucleus, influencing how genes are expressed.