BAF (Bromodomain and Extraterminal Domain) family

The BAF (Bromodomain and Extraterminal Domain) family consists of proteins that play a key role in regulating gene activity by modifying the structure of DNA packaging in cells. They recognize specific chemical marks on histones (proteins around which DNA winds), influencing how tightly or loosely DNA is wound. This affects whether genes are turned on or off, impacting processes like growth, development, and cell division. BAF proteins are critical for normal cellular function, and mutations in them can contribute to diseases such as cancer and developmental disorders.