bacterial artificial chromosomes (BACs)

Bacterial artificial chromosomes (BACs) are engineered DNA molecules used as tools in genetics research. They are derived from bacterial plasmids but designed to carry large segments of DNA—up to hundreds of thousands of base pairs. BACs can replicate within bacteria, making it easier for scientists to study and manipulate large genes or genomic regions. They are valuable for tasks like genome sequencing, gene mapping, and studying genetic variations, providing a stable and efficient way to handle and analyze sizable pieces of DNA in laboratory settings.