B-cell depletion

B-cell depletion refers to reducing the number of B cells, a type of white blood cell involved in the immune response. B cells produce antibodies that identify and fight infections. In certain medical treatments, such as for autoimmune diseases or some cancers, doctors use drugs to decrease B cells to help control overactive immune responses or target cancer cells. This process can temporarily weaken the immune system's ability to fight infections, so patients may be more susceptible to illnesses during depletion. B-cell depletion is a carefully managed therapy aimed at restoring immune balance or fighting disease more effectively.