Avram Hershko

Avram Hershko is an Israeli scientist renowned for discovering the role of the proteasome, a complex within cells that degrades unnecessary or damaged proteins. His work, for which he shared the 2004 Nobel Prize in Chemistry, helped to clarify how cells maintain protein balance and regulate functions critical to health. Understanding proteasome function has advanced knowledge of diseases like cancer and neurodegenerative disorders, and has informed the development of targeted therapies. Hershko's research has significantly contributed to cell biology and medicine by unveiling fundamental mechanisms of protein regulation.