autoinflammatory syndrome

Autoinflammatory syndromes are medical conditions where the immune system, which normally protects the body from infections, becomes overactive without an apparent infection or external cause. This leads to repeated episodes of inflammation, causing symptoms like fever, rashes, joint pain, and swelling. These syndromes are often linked to genetic mutations that affect how the immune system regulates itself. Unlike autoimmune diseases, where the immune system targets the body's own tissues, autoinflammatory syndromes involve innate immune responses that are improperly activated, resulting in inflammation and discomfort. Treatment typically focuses on reducing inflammation and managing symptoms.