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Autoimmunity and Rheumatoid Arthritis

Autoimmunity occurs when the immune system mistakenly attacks the body’s own cells, thinking they are foreign invaders. Rheumatoid arthritis (RA) is a chronic autoimmune disease primarily affecting the joints, where the immune system targets the synovium, the lining of the joints. This leads to inflammation, pain, and, if untreated, can result in joint damage and deformity. Symptoms often include stiffness, swelling, and fatigue. RA can also affect other body systems, making it more than just a joint issue. Treatment typically involves medications to reduce inflammation and manage symptoms, aiming to improve quality of life.