Autoimmune Lymphoproliferative Syndrome (ALPS)

Autoimmune Lymphoproliferative Syndrome (ALPS) is a rare genetic disorder that affects the immune system. In people with ALPS, the body produces too many lymphocytes, a type of white blood cell, leading to enlarged lymph nodes and spleen. The immune system mistakenly attacks healthy cells, resulting in autoimmune problems. Symptoms may include persistent infections, fatigue, and increased risk of certain cancers. ALPS is often caused by mutations in specific genes that regulate immune cell survival. Early diagnosis and management can help control symptoms and improve quality of life for those affected by the condition.