AUC/MIC ratio

The AUC/MIC ratio is a measurement used to evaluate how effectively an antibiotic fights bacteria. AUC (Area Under the Curve) represents the total exposure of the bacteria to the drug over time, while MIC (Minimum Inhibitory Concentration) is the smallest amount needed to stop bacterial growth. A higher AUC/MIC ratio generally indicates better drug effectiveness, as the bacteria are exposed to ample drug levels for enough time to eliminate them. Clinicians use this ratio to optimize dosing, balancing efficacy with minimizing side effects, ensuring the antibiotic is used in the most effective way.