Atypical Hemolytic Uremic Syndrome (aHUS)

Atypical Hemolytic Uremic Syndrome (aHUS) is a rare, serious condition where the immune system mistakenly damages tiny blood vessels, leading to the destruction of red blood cells, low platelets, and kidney failure. Unlike typical HUS usually triggered by infections, aHUS involves abnormal activation of a part of the immune system called the complement system. This overactivation causes ongoing clot formation and damage to organs, primarily the kidneys. aHUS requires prompt treatment, often with medications that control the complement system, to prevent lasting organ damage and improve outcomes.