ATP depletion

ATP depletion occurs when the body's cells lack sufficient energy molecules called adenosine triphosphate (ATP), which power nearly all cellular processes. ATP is generated primarily through food breakdown and used for functions like muscle contraction, nerve signaling, and maintenance of cell health. When energy demands surpass supply—due to poor nutrition, oxygen shortage, or disease—ATP levels drop. This depletion impairs cell function, leading to fatigue, weakness, and potential cell damage or death if sustained. Essentially, ATP depletion starves cells of the energy they need for normal operation, compromising overall health.