Asymptomatic Carotid Surgery Trial (ACST)

The Asymptomatic Carotid Surgery Trial (ACST) was a major research study that evaluated the effectiveness of surgery to prevent strokes in people without symptoms of carotid artery blockage. The trial aimed to determine if surgical procedures, like carotid endarterectomy, could reduce the risk of future strokes compared to medical management alone. Results indicated that surgery can significantly lower stroke risk in certain asymptomatic patients, helping clinicians make better treatment decisions. The ACST has played a crucial role in guiding recommendations for managing carotid artery disease, balancing the benefits and risks of surgery.