Array CGH (Comparative Genomic Hybridization)

Array Comparative Genomic Hybridization (Array CGH) is a lab technique used to analyze a person's DNA for changes in the number of copies of specific genes or chromosome regions. It compares the patient’s DNA to a reference sample, highlighting deletions or duplications that may be linked to genetic conditions. This method uses microarrays—small slides with many DNA probes—to detect genetic imbalances across the genome quickly and accurately, aiding in diagnosis and understanding of genetic disorders without needing to grow cells or analyze chromosomes directly.