Apligraf

Apligraf is a biologically engineered skin substitute used to help heal difficult or non-healing wounds, such as diabetic foot ulcers or venous leg ulcers. It contains living human skin cells cultured on a collagen matrix, which mimics natural skin structure. These living cells promote healing by encouraging tissue growth, reducing infection risk, and restoring skin function. Apligraf is applied to the wound site and acts as temporary skin, supporting the body's natural healing process until new, permanent skin develops. It is used under medical supervision to improve healing outcomes in cases where traditional treatments may be insufficient.