Antisperm Antibodies

Antisperm antibodies are proteins made by the immune system that mistakenly target and attack a man's sperm. This can happen if the body's immune system encounters sperm as foreign invaders, leading to inflammation or reduced sperm motility. When these antibodies bind to sperm, they can impair the sperm's ability to travel and fertilize an egg, potentially causing infertility. In some cases, these antibodies can develop after injury, surgery, or infection in the reproductive system. Testing for antisperm antibodies can help identify this issue in men experiencing infertility problems.