Anti-Neutrophil Cytoplasmic Antibody (ANCA)-associated vasculitis

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a group of rare autoimmune diseases where the body’s immune system mistakenly attacks its own blood vessels, leading to inflammation. This can damage various organs, especially the kidneys, lungs, and nerves. ANCA are antibodies that target proteins in neutrophils, a type of white blood cell. The exact cause is unclear, but symptoms may include fatigue, fever, and organ-specific issues. Diagnosis typically involves blood tests and imaging, while treatment often includes immunosuppressive medications to reduce inflammation and prevent damage. Early detection and management are crucial for improving outcomes.