Anti-myeloperoxidase (MPO) antibody

Anti-myeloperoxidase (MPO) antibody is an immune protein that mistakenly targets and attacks myeloperoxidase, an enzyme found in certain white blood cells involved in fighting infections. This autoimmune response can cause inflammation and damage in blood vessels and tissues, leading to conditions like vasculitis. The presence of MPO antibodies in the blood helps doctors diagnose specific types of vasculitis, such as microscopic polyangiitis. Testing for MPO antibodies provides valuable information about the immune system's role in these diseases and guides appropriate treatment strategies.