anti-CCP (anti-cyclic citrullinated peptide) antibodies

Anti-CCP antibodies are proteins produced by the immune system that specifically target citrullinated proteins—altered forms of normal proteins—in the body. Their presence is strongly associated with rheumatoid arthritis (RA), an autoimmune disease where the immune system mistakenly attacks joints. Detecting anti-CCP antibodies helps in diagnosing RA, often before significant joint damage occurs. These antibodies are highly specific to RA, meaning they are rarely found in other conditions, and their presence can also indicate a more aggressive disease course. Testing for anti-CCP antibodies is a valuable tool for healthcare providers in confirming and managing rheumatoid arthritis.