Anfinsen's dogma

Anfinsen's dogma states that the three-dimensional structure of a protein, which determines its function, is inherently encoded in its amino acid sequence. Essentially, if you have the right conditions, a protein can spontaneously fold into its correct shape solely based on its sequence, without needing external help. This principle highlights that a protein's information for its structure is contained within its primary structure, and proper folding is a natural process driven by chemical interactions among amino acids.