Image for Anderson's Theory on Celiac Mechanisms

Anderson's Theory on Celiac Mechanisms

Anderson's theory on celiac disease suggests that the immune system mistakenly identifies gluten—a protein in wheat, barley, and rye—as a harmful invader. This triggers an immune response that damages the lining of the small intestine, impairing nutrient absorption. The theory emphasizes that genetic factors, such as specific HLA genes, make some individuals more susceptible. It also highlights that environmental triggers and immune system malfunction contribute to the development of celiac disease, leading to symptoms like diarrhea, weight loss, and nutritional deficiencies when gluten is consumed.