alpha-2 adrenergic agonists

Alpha-2 adrenergic agonists are medications that target specific receptors in the nervous system, called alpha-2 receptors. When they activate these receptors, they reduce the release of certain stress hormones like norepinephrine. This action helps lower blood pressure, reduce muscle tension, and calm the nervous system. These drugs are often used to treat high blood pressure, sedation, or manage withdrawal symptoms. Examples include clonidine and dexmedetomidine. They work by diminishing sympathetic nervous system activity, leading to a calming effect on the body.