African histiocytosis

African histiocytosis is a rare condition where certain immune cells, called histiocytes, build up abnormally in tissues, especially in the skin and bones. This buildup causes inflammation, swelling, and often skin changes like nodules or patches. The exact cause isn’t well understood, but it’s believed to involve an abnormal immune response. Symptoms vary depending on affected areas and may include skin lesions, bone pain, or lymph node enlargement. Diagnosis typically involves biopsy and microscopic examination. Treatment options include medications to control inflammation and immune activity. Though rare, early diagnosis helps manage symptoms and improves outcomes.