
Advanced PAH-specific Drug Therapies
Advanced PAH-specific drug therapies are specialized treatments for pulmonary arterial hypertension (PAH), a condition where blood pressure in the lung arteries is abnormally high. These medications work by relaxing and expanding the blood vessels, reducing pressure and improving blood flow. They include drugs like endothelin receptor antagonists, phosphodiesterase-5 inhibitors, prostacyclin analogs, and soluble guanylate cyclase stimulators. These therapies are tailored to the severity of the disease, often used when simpler treatments are insufficient, aiming to improve symptoms, increase exercise capacity, halt disease progression, and enhance overall quality of life.