ACPA

ACPA, or Anti-Citrullinated Protein Antibody, is a type of antibody often found in the blood of people with rheumatoid arthritis (RA). These antibodies target certain proteins that have undergone a chemical change called citrullination. The presence of ACPA is useful for diagnosing RA, as it's highly specific to the disease, and can sometimes indicate a more severe disease course. Detecting ACPA helps doctors confirm the diagnosis and develop an appropriate treatment plan, making it a valuable tool in managing rheumatoid arthritis effectively.