ACMG Standards and Guidelines

The ACMG Standards and Guidelines are a set of recommendations used by genetic professionals to interpret and report genetic test results accurately. They help determine whether a genetic variant is likely to cause a disease, be harmless, or uncertain. These guidelines ensure consistent, evidence-based assessments across laboratories, improving the reliability of genetic information for diagnosis, management, and counseling. By providing a structured approach, the ACMG standards support integrating genetics into patient care responsibly and effectively.