ACMG guidelines for NIPT

The ACMG guidelines for Non-Invasive Prenatal Testing (NIPT) provide standards for using the test to screen for certain fetal chromosome abnormalities, like Down syndrome. They recommend understanding that NIPT is a highly accurate screening tool, but not a diagnostic test. Positive results should be confirmed with more definitive testing, such as amniocentesis. The guidelines emphasize thorough counseling before and after testing to help expectant parents interpret results, consider options, and understand limitations. Overall, they promote responsible use of NIPT to ensure informed decision-making, integrating it appropriately into prenatal care.